ORGANISATION/COMPANYEindhoven University of Technology (TU/e)
RESEARCHER PROFILEFirst Stage Researcher (R1)
APPLICATION DEADLINE31/08/2017 22:00 - UTC
TYPE OF CONTRACTPermanent
HOURS PER WEEK38
The group Molecular Biosensing for Medical Diagnostics (MBx, see www.tue.nl/mbx) at Eindhoven University of Technology (TU/e) creates ideas and generates scientific insights in the area of molecular biosensing with single-molecule resolution. This involves the engineering of molecular constructs for sensing applications (using protein, nucleic-acid, and protein-DNA technologies), methods to biofunctionalize nanoparticles, the development of novel single-molecule measurement methods, optical microscopies, particle characterization techniques, plasmonic effects, particle actuation principles, signal processing, and simulations. The research leads to novel methods for molecular biosensing, insights into protein function within complex and crowded environments, and novel routes into point-of-care and patient monitoring applications. The MBx group initiated and organizes the international competition on Sensors for Health (www.sensus.org). Laboratories are shared with the Chemical Biology research group (www.tue.nl/cb) and the Institute for Complex Molecular Systems (www.tue.nl/icms).
The PhD position is part of a collaboration between TU/e, Wageningen University and Research Centre (WUR), and six companies: Philips, Future Diagnostics, HyTest, Scienion, Stratec, and Synaffix. The PhD project at TU/e focuses on the development, characterization and understanding of surfaces for biosensing with single-molecule resolution. We propose a 'Molecular Gecko' approach, wherein antibodies with precisely defined linker polypeptides (provided by WUR) are attached to otherwise anti-fouling polymer-coated sensor surfaces. This new technology will be investigated and later demonstrated in experiments with medically-relevant biomarkers.
€ 2191 per month initially, to € 2801 in the fourth year.
More information can be obtained from Prof. M.W.J. Prins, Molecular Biosensing for Medical Diagnostics, Dept. of Applied Physics and Dept. of Biomedical Engineering, Eindhoven University of Technology. Phone +31 40 274 4018, email@example.com.
If you are interested in this position, please send your application by using the 'Apply now'- button on this page. Your application must contain the following documents (in PDF format): letter of motivation, curriculum vitae, transcripts of BSc and MSc degrees (with courses and grades), copy of BSc and MSc theses, and contact information of two references.
Web site for additional job details
We are looking for enthusiastic candidates who are in an MSc program or who already have an MSc degree, preferably in Chemistry, Physics, Biomedical Engineering, or Nanotechnology. An interest in Physical Chemistry or Biophysics is required. Experience in advanced microscopies or single-molecule methods is a plus.
EURAXESS offer ID: 218294
Posting organisation offer ID: 40450