18/06/2019

Engineer in Bioinformatics

This job offer has expired


  • ORGANISATION/COMPANY
    Centre Léon Bérard
  • RESEARCH FIELD
    Computer scienceInformatics
    Medical sciences
  • RESEARCHER PROFILE
    Recognised Researcher (R2)
    Established Researcher (R3)
  • APPLICATION DEADLINE
    15/09/2019 12:00 - Europe/Athens
  • LOCATION
    France › Lyon
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    35
  • OFFER STARTING DATE
    01/10/2019

Description:

We offer an 18-months position for a Engineer in the field of bioinformatics applied to Next Generation Sequencing. The project aims at identifying the molecular alterations and defining the precise tumour subtype of a large series of “still unclassified” sarcomas using multidimensional and integrative data analysis approaches. The successful candidate will mine WTS, WES and methylome data to identify known and novel oncogenic alterations as well as to achieve robust classification. Results from these analyses will be coupled to clinical and pathological information, to identify specific patterns correlated with clinical information (status, relapse or metastasis). The candidate will also participate to the other projects of the group, especially involving ChiP-seq and single cell bioinformatics analyses.

Requirements:

Applicants should have at least a master’s degree in bioinformatics, with prior experience in Next Generation Sequencing analyses. A good knowledge in statistics and in programming (bash, R, perl, C or python) is mandatory. Experience in machine learning techniques is required and knowledge in cancer biology and genetics would be an advantage but is not mandatory. Good communication skills in English are also required.

The environment:

The “Biology of Rare Sarcomas” group aims at identifying and investigating new alterations in sarcomas to unravel new oncogenic mechanisms. We are affiliated to the Cancer Research Centre of Lyon (CRCL – INSERM U1052 / CNRS 5286) and to the Centre Léon Bérard’s Department of Translational Research and Innovation. The CRCL is amongst the most prestigious cancer research center in France and the CLB is a major reference cancer center, especially for sarcomas. Our group is therefore composed of both researchers, clinicians and pathologists. The successful applicant will also strongly interact with the "Gilles Thomas" bioinformatics facility (Dir. Alain Viari).

Duration of this position is 18 months (potentially renewable once). The successful applicant is expected to start in October/November 2019.

Please send a cover letter describing your research interests, a detailed CV mentioning skills and achievements and reference letters to: franck.tirode@lyon.unicancer.fr

Required Research Experiences

  • RESEARCH FIELD
    Computer scienceInformatics
  • YEARS OF RESEARCH EXPERIENCE
    1 - 4

Offer Requirements

  • REQUIRED EDUCATION LEVEL
    Computer science: Master Degree or equivalent
  • REQUIRED LANGUAGES
    ENGLISH: Good
    FRENCH: Good

Skills/Qualifications

Applicants should have at least a master’s degree in bioinformatics, with prior experience in Next Generation Sequencing analyses. A good knowledge in statistics and in programming (bash, R, perl, C or python) is mandatory. Experience in machine learning techniques is required and knowledge in cancer biology and genetics would be an advantage but is not mandatory.

Work location(s)
1 position(s) available at
Centre Léon Bérard
France
Lyon
69008
28 Rue Laennec

EURAXESS offer ID: 418602

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